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Title:
Tissue distribution and residue depletion of oxytetracycline in sea bream (Sparus aurata) and sea bass (Dicentrarchus labrax) after oral administration.
Authors:
Malvisi J, della Rocca G, Anfossi P, Giorgetti G (1996)
Drug:
Oxytetracycline
Fish species:
Seabream, gilthead
Date:
1996
t1/2-hr:
86
Sample:
muscle
Ave Weight (gm):
60
Ave Water temp (°C):
26
Water:
Saltwater
Dosage:
7.5 g/kg 14 d
Route:
PO
Comments:
*The t1/2 of the two elimination phases; The highest [] in skin and liver >vertebrae>muscle. 19- 25 C, until 20th day after medication: 24- 28 C. T1/2=3.6 d with <0.1ug/g at 20 d, the prolonged t1/2=51.6 d, sea water in Lagoon of Grado - may be brackish with substantial fluctuations in salinity.
Citation:
Aquaculture 147: 159-168
Link:
http://dx.doi.org/10.1016/S0044-8486(96)01383-X
Genus Species:
Sparus aurata
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
3.6 d51.6 d prolonged phase
Wt gm-detail:
50- 70 g
Water temp (°C)-detail:
19- 25 C, until 20th day after medication: 24- 28 C
Dosage-detail:
7.5 g/kg for 14d
Method:
HPLC
Authors-red:
Malvisi J, della Rocca G, Anfossi P, Giorgetti G (1996)
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