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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Drug uptake and disposition in fish: An autoradiographic study with dihydrostreptomycin in the rainbow trout.
Authors:  Czerwinska K, Sunk RB, Sognen E
Drug:  Dihydrostreptomycin
Fish species:  Trout, rainbow
Date:  1990
Sample:  liver
Ave Weight (gm):  30
Ave Water temp (°C):  6
Water:  Freshwater
Dosage:  0.125 mg sd
Route:  IV
Comments:  DHS was relatively rapidly cleared from the body. DHS activity in blood, gills, kidney, liver, intestine tract-caeca at 1 hr. By 8 hr decreased activity in blood, none in kidney, but high in gall bladder and intestine. Very little in muscle, some in skin.. (3H)DHS.
Citation:  Acta Pharmaceutica Nordica 2:6:377-386
Link:  http://www.cabdirect.org/abstracts/19912216788.html  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antibiotic-Aminoglycoside
Wt gm-detail:  30 g
Water temp (°C)-detail:  5.5-6 C
Dosage-detail:  0.125 mg sd
Method:  Rad/Whole body Autoradiography
Authors-red:  Czerwinska K, Sunk RB, Sognen E