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U.S. Department of Health and Human Services

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Title:  The distribution of 3H-Tetracycline after a single, oral dose in the rainbow trout (Salmo Gairdneri) as observed by whole body autoradiography.
 
Authors:  Ingebrigtsen K, Nafstad I, Maritim A
 
Drug:  Tetracycline
 
Fish species:  Trout, rainbow
 
Date:  1985
 
Sample:  whole body
 
Ave Weight (gm):  200
 
Ave Water temp (°C):  6
 
Water:  Freshwater
 
Dosage:  200 uCi
 
Route:  PO
 
Comments:  Labelled tetracycline given in capsule, Sagital whole-body sections cut from different levels, 2 days = negligible absorption, radioactivity limited to gastrointestinal content, 7 days = radiolabeled material distributed througout body highest in: bile, liver, skin, bone, uveal tract, 21 days = bile and mucosal lining high degree of labelling. Skeleton retained label but only trace signal left in liver and kidney. Tetracycline (3H).
 
Citation:  Acta vet. Scand. 26:428-430
 
Link:  http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=4096329&dopt=Citation  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Tetracycline
 
Wt gm-detail:  200 +/- 20 g
 
Water temp (°C)-detail:  6 C
 
Dosage-detail:  200 uCi in 0.5 g feed
 
Method:  Rad/Whole body Autoradiography
 
Authors-red:  Ingebrigtsen K, Nafstad I, Maritim A
 
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