• Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail

  • Print
  • Share
  • E-mail
Title:  The distribution of 3H-Tetracycline after a single, oral dose in the rainbow trout (Salmo Gairdneri) as observed by whole body autoradiography.
Authors:  Ingebrigtsen K, Nafstad I, Maritim A
Drug:  Tetracycline
Fish species:  Trout, rainbow
Date:  1985
Sample:  whole body
Ave Weight (gm):  200
Ave Water temp (°C):  6
Water:  Freshwater
Dosage:  200 uCi
Route:  PO
Comments:  Labelled tetracycline given in capsule, Sagital whole-body sections cut from different levels, 2 days = negligible absorption, radioactivity limited to gastrointestinal content, 7 days = radiolabeled material distributed througout body highest in: bile, liver, skin, bone, uveal tract, 21 days = bile and mucosal lining high degree of labelling. Skeleton retained label but only trace signal left in liver and kidney. Tetracycline (3H).
Citation:  Acta vet. Scand. 26:428-430
Link:  http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=4096329&dopt=Citation  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antibiotic-Tetracycline
Wt gm-detail:  200 +/- 20 g
Water temp (°C)-detail:  6 C
Dosage-detail:  200 uCi in 0.5 g feed
Method:  Rad/Whole body Autoradiography
Authors-red:  Ingebrigtsen K, Nafstad I, Maritim A