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Title:
Tissue levels of oxolinic acid after oral and intravascular administration to freshwater and seawater rainbow trout.
Authors:
Ishida N
Drug:
Oxolinic acid
Fish species:
Trout, rainbow
Date:
1992
Sample:
blood, serum
Ave Weight (gm):
472
Ave Water temp (°C):
16
Water:
Saltwater
Dosage:
40 mg/kg
Route:
PO
Comments:
Tissue concentrations of the drug peaked at 48h and were detectable for at least 244h vs undetectable by 72h in saltwater group. Glucuronide metabolites in bile of both salt and freshwater groups. Residue 24h=1.4, 72h=nd ug/gm.
Citation:
Aquaculture 102:9-15
Link:
http://dx.doi.org/10.1016/0044-8486(92)90284-R
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
<72 h est
Wt gm-detail:
472 g
Water temp (°C)-detail:
16 C
Dosage-detail:
40 mg/kg
Method:
HPLC
Authors-red:
Ishida N
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