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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Pharmacokinetics and bioavailability of flumequine and oxolinic acid after various routes of administration to Atlantic salmon in seawater.
Authors:  Rogstad A, Ellingsen OF, Syvertsen C
Drug:  Oxolinic acid
Fish species:  Salmon, Atlantic
Date:  1993
t1/2-hr:  90
est:  est
Sample:  blood, plasma
Ave Weight (gm):  425
Ave Water temp (°C):  5
Water:  Saltwater
Dosage:  50 mg/kg sd
Route:  PO
Comments:  Bioavailability=25% AUC = 58.9 ug h/ml. C-max=1.17 at 24h. Salinity 30 ppt.
Citation:  Aquaculture 110:207-220
Link:  http://www.sciencedirect.com/science/article/pii/004484869390369A  Opens a new window
Genus Species:  Salmo salar
Drug Class:  Antibiotic-Quinolone
t1/2-detail:  90 h est
Wt gm-detail:  425 g
Water temp (°C)-detail:  5+/-0.2 C
Dosage-detail:  50 mg/kg sd
Method:  HPLC
Authors-red:  Rogstad A, Ellingsen OF, Syvertsen C