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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics, tissue distribution, and metabolism of nitrofurantoin in the channel catfish (Ictalurus punctatus).
 
Authors:  Stehly GR, Plakas SM (1993)
 
Drug:  Nitrofurantoin
 
Fish species:  Catfish, channel
 
Date:  1993
 
t1/2-hr:  72
 
est:  est
 
Sample:  kidney, cranial
 
Ave Weight (gm):  700
 
Ave Water temp (°C):  25
 
Water:  Freshwater
 
Dosage:  1 mg/kg sd
 
Route:  PO
 
Comments:  14C-Nitrofurantoin. Total residue ug/g 4h=0.24, 1d=0.15, 2d=0.14, 3d=0.12. Urinary catheterized fish. t1/2 est from table.
 
Metabolites:  5 metabolites
 
Citation:  Aquaculture 113:1-10
 
Link:  http://dx.doi.org/10.1016/0044-8486(93)90335-V  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antibiotic-Furan
 
t1/2-detail:  < 72 h, est from table.
 
Wt gm-detail:  0.4-1.0 kg
 
Water temp (°C)-detail:  25 C
 
Dosage-detail:  1 mg/kg sd
 
Method:  HPLC-Rad
 
Authors-red:  Stehly GR, Plakas SM (1993)
 
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