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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Pharmacokinetics of sulphamonomethoxine and sulphadimethoxine following oral administration to cultured rainbow trout (Oncorhynchus mykiss).
Authors:  Uno K, Aoki T, Ueno R (1993b)
Drug:  Sulfadimethoxine
Fish species:  Trout, rainbow
Date:  1993
t1/2-hr:  72
Sample:  muscle
Ave Weight (gm):  240
Ave Water temp (°C):  15
Water:  Freshwater
Dosage:  200 mg/kg sd
Route:  PO
Comments:  Residue ug/g max . 24 h= 5.04, 05h=nd, 1h=nd, 3h=nd, 6h=nd, 9h=0.40, 12h=0.16, 24h=5.04, 2d=2.95, 3d=2.63, 5d=0.34, 7d=nd, 10d=nd, 13d=0.13, 16d=0.17, nd after 20d.
Metabolites:  N4-A-SDM
Citation:  Aquaculture 115:209-219
Dep-time:  19 days
Link:  http://dx.doi.org/10.1016/0044-8486(93)90137-N  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antibiotic-Sulfa
t1/2-detail:  72.3 h
Wt gm-detail:  210-270 g
Water temp (°C)-detail:  15 C
Dosage-detail:  200 mg/kg sd
Method:  HPLC
Authors-red:  Uno K, Aoki T, Ueno R (1993b)