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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics of sulphamonomethoxine and sulphadimethoxine following oral administration to cultured rainbow trout (Oncorhynchus mykiss).
 
Authors:  Uno K, Aoki T, Ueno R (1993b)
 
Drug:  Sulfadimethoxine
 
Fish species:  Trout, rainbow
 
Date:  1993
 
t1/2-hr:  72
 
Sample:  muscle
 
Ave Weight (gm):  240
 
Ave Water temp (°C):  15
 
Water:  Freshwater
 
Dosage:  200 mg/kg sd
 
Route:  PO
 
Comments:  Residue ug/g max . 24 h= 5.04, 05h=nd, 1h=nd, 3h=nd, 6h=nd, 9h=0.40, 12h=0.16, 24h=5.04, 2d=2.95, 3d=2.63, 5d=0.34, 7d=nd, 10d=nd, 13d=0.13, 16d=0.17, nd after 20d.
 
Metabolites:  N4-A-SDM
 
Citation:  Aquaculture 115:209-219
 
Dep-time:  19 days
 
Link:  http://dx.doi.org/10.1016/0044-8486(93)90137-N  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  72.3 h
 
Wt gm-detail:  210-270 g
 
Water temp (°C)-detail:  15 C
 
Dosage-detail:  200 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Uno K, Aoki T, Ueno R (1993b)
 
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