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Title:
Pharmacokinetics of sulphamonomethoxine and sulphadimethoxine following oral administration to cultured rainbow trout (Oncorhynchus mykiss).
Authors:
Uno K, Aoki T, Ueno R (1993b)
Drug:
Sulfamonomethoxine
Fish species:
Trout, rainbow
Date:
1993
t1/2-hr:
201
Sample:
intestinal tract-bile
Ave Weight (gm):
240
Ave Water temp (°C):
15
Water:
Freshwater
Dosage:
300 mg/kg sd
Route:
PO
Comments:
Residues could be detected in bile for over 32 days. Max 5d=1891, 0.5h=nd, 1h=nd, 3h=11.3, 6h=68.8, 9h=377, 12h=647, 24h=943, 2d=965, 3d=1166, 5d=1891, 7d=1010,10d=1775, 13d=646, 16d=991, 20d=722, 24d=361, 28d=175, 32d=224 ug/g.
Metabolites:
N4-A-sulfamonomethoxine
Citation:
Aquaculture 115:209-219
Dep-time:
132 days
Link:
http://dx.doi.org/10.1016/0044-8486(93)90137-N
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
201 h
Wt gm-detail:
210-270 g
Water temp (°C)-detail:
15 C
Dosage-detail:
300 mg/kg sd
Method:
HPLC
Authors-red:
Uno K, Aoki T, Ueno R (1993b)
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