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Title:
Exploratory bioavailability and pharmacokinetic studies of sulphadimethoxine and ormetoprim in the penaeid shrimp, Penaeus vannamei.
Authors:
Park ED, Lightner DV, Milner N, Mayersohn M, Park DL, Gifford JM, Bell TA
Drug:
Ormetoprim
Fish species:
Shrimp, whiteleg
Date:
1995
t1/2-hr:
9
Sample:
blood, hemolymph
Ave Weight (gm):
20
Ave Water temp (°C):
26
Water:
Saltwater
Dosage:
42 mg/kg sd
Route:
PO
Comments:
Bioavailability 32 %, Residues below detectable limit by 24 hr.
Protein binding:
0.12
Citation:
Aquaculture 130:113-128
Link:
http://dx.doi.org/10.1016/0044-8486(94)00217-C
Genus Species:
Litopenaeus vannamei
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
8.3 h
Wt gm-detail:
17-22 g
Water temp (°C)-detail:
26+/-1 C
Dosage-detail:
42 mg/kg sd
Method:
HPLC
Authors-red:
Park ED, Lightner DV, Milner N, Mayersohn M, Park DL, Gifford JM, Bell TA
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