Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Pharmacokinetics and metabolism of sulphamonomethoxine in rainbow trout (Oncorhynchus mykiss) and yellowtail (Seriola quinqueradiata) following bolus intravascular administration.
 
Authors:  Uno K, Aoki T, Ueno R, Maeda I
 
Drug:  Sulfamonomethoxine
 
Fish species:  Trout, rainbow
 
Date:  1997
 
t1/2-hr:  31
 
Sample:  blood, serum
 
Ave Weight (gm):  171
 
Ave Water temp (°C):  15
 
Water:  Freshwater
 
Dosage:  100 mg/kg sd
 
Route:  IV
 
Comments:  protein binding for AcSMM= 9.5 +/- 3.6% Vd= 0.83 L/kg; Vc= 0.3 L/kg, alpha = 0.43h.
 
Protein binding:  6.4 +/- 2.3%
 
Cl:  0.0185 L/kg/h
 
Vc:  0.3 L/kg
 
Vd:  0.83 L/kg
 
Metabolites:  N4-A-sulphamonomethoxine
 
Citation:  Aquaculture 153:1-8
 
Link:  http://dx.doi.org/10.1016/S0044-8486(97)00012-4  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  30.9 h
 
Wt gm-detail:  171 +/- 15 g
 
Water temp (°C)-detail:  15.0 +/- 0.3 C
 
Dosage-detail:  100 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Uno K, Aoki T, Ueno R, Maeda I
 
-
-