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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Depletion study of fenbendazole in rainbow trout (Oncorhynchus mykiss) after oral and bath treatment.
Authors:  Iosifidou EG, Haagsma N, Tanck MWT, Boon JH, Olling M
Drug:  Fenbendazole
Fish species:  Trout, rainbow
Date:  1997
t1/2-hr:  96
est:  est
Sample:  skin
Ave Weight (gm):  154
Ave Water temp (°C):  12
Water:  Freshwater
Dosage:  6 mg/kg sd
Route:  PO
Comments:  Metabolite - FBZ-SO -12 h after treatment median concentration=11 µg/kg, 24 h26 µg/kg, 48 h =14 µg/kg, 96 h = 11 µg/kg. Undetected in 3 of 5 fish at 72 hr, and undetected in 5 of 5 fish at 120 hr.
Metabolites:  FBZ-SO-oxfendazole
Citation:  Aquaculture 154:191-199
Dep-time:  5 d
Link:  http://dx.doi.org/10.1016/S0044-8486(97)00051-3  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antiparasitic-Benzimidazole
t1/2-detail:  < 96 h
Wt gm-detail:  154 +/-29g
Water temp (°C)-detail:  12 C
Dosage-detail:  6 mg/kg sd
Method:  HPLC
Authors-red:  Iosifidou EG, Haagsma N, Tanck MWT, Boon JH, Olling M