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Title:
Pharmacokinetics of oxytetracycline in Arctic charr (Salvelinus alpinus L.) in freshwater at low temperature.
Authors:
Haug T, Hals PA
Drug:
Oxytetracycline
Fish species:
Char, Arctic
Date:
2000
t1/2-hr:
266
Sample:
blood, plasma
Ave Weight (gm):
454
Ave Water temp (°C):
6
Water:
Freshwater
Dosage:
10 mg/kg sd
Route:
IVC
Comments:
Vd-area = 2.57 +/- 1.03 L/kg, Vd(steady state)= 1.98 +/- 0.60 L/kg Vc= 0.13 +/- 0.03 L/kg, ²= 16.5, ³= 266.3
Cl:
0.007 L/kg/h
Vc:
0.13 +/- 0.03 L/kg
Vd:
1.98 +/- 0.60 L/kg
Citation:
Aquaculture 186:175-191
Link:
http://dx.doi.org/10.1016/S0044-8486(99)00376-2
Genus Species:
Salvelinus alpinus alpinus
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
²= 16.5³= 266.3
Wt gm-detail:
454 +/- 149 g
Water temp (°C)-detail:
6.3 C
Dosage-detail:
10 mg/kg sd
Method:
HPLC
Authors-red:
Haug T, Hals PA
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