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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics and metabolism of miloxacin in cultured eel.
 
Authors:  Ueno R, Okada Y, Tatsuno T
 
Drug:  Miloxacin
 
Fish species:  Eel, Japanese
 
Date:  2001
 
t1/2-hr:  240
 
est:  est
 
Sample:  intestinal tract-bile
 
Ave Weight (gm):  175
 
Ave Water temp (°C):  27
 
Water:  Not Specified
 
Dosage:  60 mg/kg sd
 
Route:  PO
 
Comments:  Metabolite Mean residues: Max Day 2= 289 ug/ml, 12 d= 128, Terminal Day 20 =1.01.
 
Metabolites:  5,8-dihydro-8-oxo-2H-1,3-dioxolo-[4,5-g]quinoline-7-carboxylic acid (M-1)
 
Citation:  Aquaculture 193: 11-24
 
Link:  http://dx.doi.org/10.1016/S0044-8486(00)00475-0  Opens a new window
 
Genus Species:  Anguilla japonica
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  240 h est
 
Wt gm-detail:  175 g
 
Water temp (°C)-detail:  27 C
 
Dosage-detail:  60 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Ueno R, Okada Y, Tatsuno T
 
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