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Title:
Comparative pharmacokinetics of oxytetracycline in eel and its fate in a closed aquatic environment.
Authors:
Ueno R, Kinoshita A, Wakabayashi J
Drug:
Oxytetracycline
Fish species:
Eel, Japanese
Date:
2004
t1/2-hr:
192
est:
est
Sample:
blood, serum
Ave Weight (gm):
158
Ave Water temp (°C):
27
Water:
Not specified
Dosage:
50 mg/kg sd
Route:
PO
Comments:
Laboratory fish. C-max 0.77ug/ml at 1d post dose, declined to 0.1 by 15d, nd by 20 d. T1/2 est from graph 8d. Bioavail= 0,69%..
Cl:
0.00298 L/kg/h
Vc:
0.13 L/kg
Vd:
0.45 L/kg
Citation:
Aquaculture 235:53-63
Link:
http://dx.doi.org/10.1016/S0044-8486(03)00449-6
Genus Species:
Anguilla japonica
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
192h est
Wt gm-detail:
158 g
Water temp (°C)-detail:
27 C
Dosage-detail:
50 mg/kg sd
Method:
HPLC
Authors-red:
Ueno R, Kinoshita A, Wakabayashi J
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