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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetics of oxytetracycline in black tiger shrimp, Penaeus monodon, and the effect of cooking on the residues.
 
Authors:  Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
 
Drug:  Oxytetracycline
 
Fish species:  Shrimp, giant tiger prawn (black tiger)
 
Date:  2006
 
t1/2-hr:  16
 
Sample:  blood, hemolymph
 
Ave Weight (gm):  23
 
Ave Water temp (°C):  30
 
Water:  Brackish
 
Dosage:  10 mg/kg sd
 
Route:  IS
 
Comments:  AUC=258 t1/2 alpha=0.2h, beta = 16.2 h. Residues from graph ug/ml, wd 0.5d=5, 1d=3, 2d=1, 3d=0.3, 4d=0.11, 5d=0.1. Vss=869 ml/kg
 
Cl:  38.7mg/kg/h
 
Vc:  217 ml/kg
 
Vd:  869 ml/kg
 
Citation:  Aquaculture 254:24-31
 
Link:  http://dx.doi.org/10.1016/j.aquaculture.2005.10.031  Opens a new window
 
Genus Species:  Penaeus monodon
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  alpha=0.20h, beta=16.2 h
 
Wt gm-detail:  22.9+/-4.9g
 
Water temp (°C)-detail:  29-30 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
 
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