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U.S. Department of Health and Human Services

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Title:  Oxytetracycline residues in cultivated marine shrimp (Litopenaeus vannamei Boone, 1931) (Crustacea, Decapoda) submitted to antibiotic treatment.
 
Authors:  Nogueira-Lima AC, Gesteira TCV, Mafezoli J
 
Drug:  Oxytetracycline
 
Fish species:  Shrimp, whiteleg
 
Date:  2006
 
t1/2-hr:  36
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  5
 
Ave Water temp (°C):  27
 
Water:  Saltwater
 
Dosage:  200 mg/kg 14 d
 
Route:  PO
 
Comments:  Laboratory experiment. Initial wt 5 g, near 6 g at end. Salinity 34.4 ppt. OTC consumption 17.61% higher than in pond experiment. Avg Cmax=17.21 ug/g after 7d, d14=11.98. t1/2-hr extrapolated from curve. Ave Conc Depletion d1=6 ug/g, d2=3.9 d17=0.17 ug/g. Slower depletion 4d to end of study. Tissues were called "abdominal tissue" - presumably muscle.
 
Citation:  Aquaculture 254:748-758
 
Dep-time:  25 d
 
Link:  http://dx.doi.org/10.1016/j.aquaculture.2005.11.021  Opens a new window
 
Genus Species:  Litopenaeus vannamei
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  36 h est
 
Wt gm-detail:  5.08+/-0.63g
 
Water temp (°C)-detail:  26.8+/-0.3 C
 
Dosage-detail:  4 gm/kg in feed 14 d
 
Method:  HPLC
 
Authors-red:  Nogueira-Lima AC, Gesteira TCV, Mafezoli J
 
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