• Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail

  • Print
  • Share
  • E-mail
Title:  Pharmacokinetics and tissue residues of difloxacdin in crucian carp (Crassius auratus) after oral administration.
Authors:  Ding F, Cao J, Ma L, Pan Q, Fang Z, Lu X
Drug:  Difloxacin
Fish species:  Carp, crucian (goldfish)
Date:  2006
t1/2-hr:  95
Sample:  blood, plasma
Ave Weight (gm):  250
Ave Water temp (°C):  10
Water:  Freshwater
Dosage:  20 mg/kg sd
Route:  PO
Comments:  AUC=1361.79 ug/mlh, time to peak 5.7 h, Cmax=9.49. Ka (absorption rate constant =0.85/h.
Cl:  0.015 l/h/kg
Vd:  2.02 l/kg
Citation:  Aquaculture 256:121-128
Link:  http://dx.doi.org/10.1016/j.aquaculture.2006.02.056  Opens a new window
Genus Species:  Carassius auratus auratus
Drug Class:  Antibiotic-Quinolone
t1/2-detail:  95
Wt gm-detail:  250 +/-30g
Water temp (°C)-detail:  10 +/-1 C
Dosage-detail:  20 mg/kg sd
Method:  HPLC
Authors-red:  Ding F, Cao J, Ma L, Pan Q, Fang Z, Lu X