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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics and the active metabolite of enrofloxacin in Chinese mitten-handed crab (Eriocheir sinensis).
 
Authors:  Tang J, Yang X-l, Zheng Z-l, Yu W-j, Hu K, Yu H-j
 
Drug:  Enrofloxacin
 
Fish species:  Crab, Chinese mitten-handed
 
Date:  2006
 
t1/2-hr:  12
 
Sample:  blood, hemolymph
 
Ave Weight (gm):  50
 
Ave Water temp (°C):  25
 
Water:  Freshwater
 
Dosage:  20 mg/kg sd
 
Route:  IM
 
Comments:  Residues -Enro. T max=0.8 h, Cmax=11 ug/ml, AUC=187. alpha t1/2=0.22. There appears to be a second absorption peak. Cipro detected within 0.5 h.
 
Cl:  0.189 l/h/kg
 
Vd:  3.35 l/kg
 
Metabolites:  Ciprofloxacin
 
Citation:  Aquaculture 260:69-76
 
Link:  http://dx.doi.org/10.1016/j.aquaculture.2006.05.036  Opens a new window
 
Genus Species:  Eriocheir sinensis
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  12 h
 
Wt gm-detail:  50 +/_10 g
 
Water temp (°C)-detail:  25+/-1 C
 
Dosage-detail:  20 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Tang J, Yang X-l, Zheng Z-l, Yu W-j, Hu K, Yu H-j
 
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