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U.S. Department of Health and Human Services

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Title:  Oxytetracycline (OTC) accumulation and elimination in hemolymph, muscle and hepatopancreas of white shirmp Litopenaeus vannamei following an OTC-feed therapeutic treatment.
 
Authors:  Gomez-Jimenez S, Espinosa-Plascencia A, Valenzuela-Villa F, Bermudez-Almada MDC
 
Drug:  Oxytetracycline
 
Fish species:  Shrimp, whiteleg
 
Date:  2008
 
Sample:  Hepatopancreas
 
Ave Weight (gm):  15
 
Ave Water temp (°C):  28.6
 
Water:  Saltwater
 
Dosage:  132 mg/kg 14d
 
Route:  PO
 
Comments:  Cmax = 194.37 +/- 16.11 ug/g. Cmax reached 2d post-exposure. OTC concentration decreased to 0.08 ug/g in all tissues after 8d of OTC withdrawal
 
Citation:  Aquaculture 274:24-29
 
Dep-time:  10d
 
Link:  http://dx.doi.org/10.1016/j.aquaculture.2007.11.017  Opens a new window
 
Genus Species:  Litopenaeus vannamei
 
Drug Class:  Antibiotic-Tetracycline
 
Wt gm-detail:  14-16 g
 
Water temp (°C)-detail:  28.6 +/- 0.2C
 
Dosage-detail:  132 mg/kg for 14d
 
Method:  HPLC
 
Authors-red:  Gomez-Jimenez S, Espinosa-Plascencia A, Valenzuela-Villa F, Bermudez-Almada MDC
 
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