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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  A comparative pharmacokinetic study of seven sulphonamides and a sulphonamide potentiator, trimethoprim, in Rainbow trout (Salmo Gairdneri, Richardson).
Authors:  McCarthy DH, Stevenson JP, Salsbury AW
Drug:  Sulfadiazine
Fish species:  Trout, rainbow
Date:  1974
t1/2-hr:  96
est:  est
Sample:  blood
Ave Weight (gm):  255
Ave Water temp (°C):  13
Water:  Freshwater
Dosage:  200 mg/kg sd
Route:  PO
Comments:  t 1/2 est from graph
Citation:  Aquaculture 4:299-303
Link:  http://dx.doi.org/10.1016/0044-8486(74)90042-8  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antibiotic-Sulfa
t1/2-detail:  96 h (est from graph)
Wt gm-detail:  220-290 g
Water temp (°C)-detail:  13 C
Dosage-detail:  200 mg/kg sd
Method:  Absorbance-Bratton&Marshall
Authors-red:  McCarthy DH, Stevenson JP, Salsbury AW