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Title:
Pharmacokinetics and bioavailabilities of 14C-ketocarotenoides, astaxanthin and canthaxanthin, in rainbow trout, Oncorhynchus mykiss.
Authors:
Choubert G, Cravedi J-P, Laurentile M
Drug:
Astaxanthin
Fish species:
Trout, rainbow
Date:
2005
t1/2-hr:
36
Sample:
blood
Ave Weight (gm):
1000
Ave Water temp (°C):
17
Water:
Freshwater
Dosage:
20 ul*
Route:
PO
Comments:
Astaxanthin-14C, ACU 6.66 ugeq/ml, Cmax=0.23 ugeq/ml, Tmax=16h. Bioavail 10-15%. Urine contained < 0.5% radioactivity over 48h. Aorta and urinary catheterized fish.
Citation:
Aquaculture Research 36:1526-1534
Link:
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2109.2005.01375.x
Genus Species:
Oncorhynchus mykiss
Drug Class:
Organic-Carotenoid
t1/2-detail:
36.13 h
Wt gm-detail:
1 kg
Water temp (°C)-detail:
17 +/- 1C
Dosage-detail:
20 ul of dissolved solution
Method:
Rad
Authors-red:
Choubert G, Cravedi J-P, Laurentile M
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