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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Internal redistribution of radiolabelled silver among tissues of rainbow trout (Oncorhynchus mykiss) and European eel (Anguilla anguilla): the influence of silver speciation.
 
Authors:  Hogstrand C, Grosell M, Wood CM, Hansen H
 
Drug:  Silver-CL (110)
 
Fish species:  Eel, European
 
Date:  2003
 
t1/2-hr:  8755
 
Sample:  blood, plasma
 
Ave Weight (gm):  60
 
Ave Water temp (°C):  0
 
Water:  Brackish
 
Dosage:  1.3 ug/l 24 h
 
Route:  BATH
 
Comments:  Comparison between silver pharmacokinetics in low and high chloride water (10 uM vs 1200 uM). (110)Ag in 1200 ug Cl water. T1/2 alpha=77h.
 
Citation:  Aquatic Toxicology 63:139-157
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12657489&query_hl=20  Opens a new window
 
Genus Species:  Anguilla anguilla
 
Drug Class:  Metal-Silver
 
t1/2-detail:  364.8 d
 
Wt gm-detail:  45-75 g
 
Water temp (°C)-detail:  not specified
 
Dosage-detail:  1.3 ug/l 24 h
 
Method:  Rad
 
Authors-red:  Hogstrand C, Grosell M, Wood CM, Hansen H
 
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