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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Accumulation and elimination of methylmercury in Atlantic cod (Gadus morhua L.) following dietary exposure.
 
Authors:  Amlund H, Lundebye AK, Berntssen MHG
 
Drug:  Methylmercury
 
Fish species:  Cod, Atlantic
 
Date:  2007
 
t1/2-hr:  9048
 
Sample:  blood
 
Ave Weight (gm):  561
 
Ave Water temp (°C):  11
 
Water:  Saltwater
 
Dosage:  0.95 +/- 0.03 ug/g in feed, 3 months
 
Route:  PO
 
Comments:  Water was provided via a flow-through system, and the amount was increased as the fish grew. Concentrations (ug/g) from graph: 10d = 0.03, 20d = 0.055, 86d =0.09, 177d = 0.02, Salinity 27 ppt. Blood accumulation from 0.01 to 0.09 in 3 months, then to 0.02 in 3 monts dep.
 
Citation:  Aquatic Toxicology 83:323-330
 
Dep-time:  >3 months
 
Link:  http://dx.doi.org/10.1016/j.aquatox.2007.05.008  Opens a new window
 
Genus Species:  Gadus morhua
 
Drug Class:  Metal-Mercury
 
t1/2-detail:  377 d
 
Wt gm-detail:  initial 325+/-93 end=796+/-196g
 
Water temp (°C)-detail:  11.1+/- 1.3 C
 
Dosage-detail:  0.95 +/- 0.03 ug/g in feed, 3 months
 
Method:  ICP, MS
 
Authors-red:  Amlund H, Lundebye AK, Berntssen MHG
 
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