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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Piperonyl butoxide enhances the bioconcentration and photoinduced toxicity of fluoranthene and benzo[a]pyrene to larvae of the grass shrimp (Palaemonetes pugio)
 
Authors:  Weinstein JE, Garner TR
 
Drug:  Piperonyl butoxide+fluoranthene
 
Fish species:  Shrimp, daggerblade grass
 
Date:  2008
 
Sample:  whole body
 
Ave Weight (gm):  0
 
Ave Water temp (°C):  22
 
Water:  Saltwater
 
Dosage:  0.250 mg/L 96h
 
Route:  BATH
 
Comments:  Fluoranthene (FLU) concentrations of 0, 0.68, 1.04, 1.84, 2.93, and 5.81 ug/L were achieved for each dose of Piperonyl butoxide (PBO). LC50=0.8ug/L. LD50=1195ng/g. PBO significantly increased the bioconcentraion of FLU in all treatments, with the greatest increases occuring in the lowest FLU treatments. Bioconcentration factor increased 35.4 fold compared to the control. Bioconcentration factor for 5.81ug FLU/L increased 1.9 fold compared to the control. PBO sign Water salinity was 20 ppt.ificantly increased the photoinduced toxicity of FLU. Water salinity was 20 ppt.
 
Citation:  Aquatic Toxicology 87: 28-36
 
Link:  http://dx.doi.org/10.1016/j.aquatox.2008.01.002  Opens a new window
 
Genus Species:  Palaemonetes pugio
 
Drug Class:  Insecticide - Piperonyl; butoxide
 
Water temp (°C)-detail:  ~22
 
Dosage-detail:  Actual dose=0.256 ug/L
 
Method:  HPLC
 
Authors-red:  Weinstein JE, Garner TR
 
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