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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  An oxytetracycline residue depletion study to assess the physiologically based pharmokinetic (PBPK) model in farmed Atlantic salmon.
 
Authors:  Brocklebank JR, Namdari R, Law FC
 
Drug:  Oxytetracycline
 
Fish species:  Salmon, Atlantic
 
Date:  1997
 
Sample:  muscle
 
Ave Weight (gm):  1500
 
Ave Water temp (°C):  9
 
Water:  Saltwater
 
Dosage:  100 mg/kg 10d, twice with 10 day control diet in between
 
Route:  PO
 
Comments:  Two periods of dosing, 10 days apart. 77 d postdosing 7 of 9 fish had detectable OTC residues in muscle. 118 d postodsing no OTC detected.
 
Citation:  Canadian Veterinary Journal 38:645-646
 
Dep-time:  118 d
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9332751&query_hl=18  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antibiotic-Tetracycline
 
Wt gm-detail:  1.5 kg
 
Water temp (°C)-detail:  6.5-11 C
 
Dosage-detail:  100 mg/kg 10d, twice with 10 day control diet in between
 
Method:  not specified
 
Authors-red:  Brocklebank JR, Namdari R, Law FC
 
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