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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Accumulation and elimination kinetics of di-, tri- and tetra chlorobiphenyls by goldfish after dietary and aqueous exposure.
 
Authors:  Bruggeman WA, Martron LBJM, Kooiman D, Hutzinger O.
 
Drug:  PCB-(2,2,5,5 Tetrachlorobiphenyl)
 
Fish species:  Carp, crucian (goldfish)
 
Date:  1981
 
t1/2-hr:  648
 
est:  est
 
Sample:  whole body
 
Ave Weight (gm):  4
 
Ave Water temp (°C):  23
 
Water:  Freshwater
 
Dosage:  Saturation of PCB with column
 
Route:  BATH
 
Comments:  Absorption: d1=43.6, d2=58.9, d3=80.0, d6=104.7, d8=97.4, d23=161. elimination: d8=124, d15=106, d27=76, d39=83, d62=74.7, d116=11.7 ug/g. 50% fish died within 7 days. K2=15/d
 
Citation:  Chemosphere 10:8:811-832
 
Link:  http://dx.doi.org/10.1016/0045-6535(81)90082-5  Opens a new window
 
Genus Species:  Carassius auratus auratus
 
Drug Class:  Organic-Chlorinated
 
t1/2-detail:  between 15-27d
 
Wt gm-detail:  4.4 g
 
Water temp (°C)-detail:  23 C
 
Dosage-detail:  Saturation of PCB with column
 
Method:  GC/MS, GC/EC
 
Authors-red:  Bruggeman WA, Martron LBJM, Kooiman D, Hutzinger O.
 
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