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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Toxicokinetics in fish: Accumulation and elimination of six chlorobenzenes by guppies.
Authors:  Könemann H, van Leeuwen K
Drug:  Chlorobenzene-(1,2,3 Tri-)
Fish species:  Guppy
Date:  1980
t1/2-hr:  96
est:  est
Sample:  whole body
Ave Weight (gm):  0.62
Ave Water temp (°C):  21
Water:  Freshwater
Dosage:  100 ng/ml 19 d
Route:  BATH
Comments:  A mixture of 6 chlorobenzenes given at once. Equilibrium reached by about 3 days. Approx residue ug/gm fat wt of fish at equilibrium=500. K2=0.45/d
Citation:  Chemosphere 9:3-19
Dep-time:  approx 20 d
Link:  http://dx.doi.org/10.1016/0045-6535(80)90150-2   Opens a new window
Genus Species:  Poecilia reticulata
Drug Class:  Organic-Chlorinated
t1/2-detail:  < 4 d est from graph
Wt gm-detail:  0.62 g
Water temp (°C)-detail:  21+/-0.5°C
Dosage-detail:  100 ng/ml 19 d
Method:  GC
Authors-red:  Könemann H, van Leeuwen K