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U.S. Department of Health and Human Services

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Title:  Influence of ormetoprim on the bioavailability, distribution, and pharmacokinetics of sulfadimethoxine in rainbow trout (Oncorhynchus mykiss).
 
Authors:  Droy BF, Tate T, Lech JJ, Kleinow KM.
 
Drug:  Sulfadimethoxine
 
Fish species:  Trout, rainbow
 
Date:  1989
 
Sample:  muscle
 
Ave Weight (gm):  540
 
Ave Water temp (°C):  14
 
Water:  Freshwater
 
Dosage:  SDM/ OMP 42/8 mg/kg sd
 
Route:  PO
 
Comments:  Oral bioavailability was 38%; Residues were: 3d pos treatment = 2.7 +/- 0.6 µg/gm 14d post= 0.5 +/- 0.2 Ormetoprim (14C).
 
Citation:  Comparative Biochemistry and Physiology 94C:1:303-307
 
Link:  http://www.sciencedirect.com/science/article/pii/0742841389901837  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Sulfa
 
Wt gm-detail:  444-640 g
 
Water temp (°C)-detail:  14C
 
Dosage-detail:  SDM/ OMP 42/8 mg/kg sd
 
Method:  HPLC-Rad
 
Authors-red:  Droy BF, Tate T, Lech JJ, Kleinow KM.
 
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