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PhishPharm - Detail
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Title:
Disposition of 14C-sarafloxacin in Atlantic salmon (Salmo salar), rainbow trout (Oncorhynchus mykiss), cod (Gadus Morhua) and turbot (Scophthalmus maximus), as demonstrated by means of whole-body autoradiography and liquid scintillation counting.
Authors:
Martinsen B, Horsberg TE, Ingebrigtsen K, Gross IL
Drug:
Sarafloxacin
Fish species:
Salmon, Atlantic
Date:
1994
t1/2-hr:
48
est:
est
Sample:
muscle
Ave Weight (gm):
109
Ave Water temp (°C):
8
Water:
Saltwater
Dosage:
10 mg/kg sd
Route:
PO
Comments:
No radioactivity was detected in blood or muscle in fish sampled later than 7d and 14d respectively, t 1/2 est from graph, Sarafloxacin (C14) Tmax-24 hr
Citation:
Diseases of Aquatic Organisms 18:37-44
Link:
http://www.int-res.com/articles/dao/18/d018p037.pdf
Genus Species:
Salmo salar
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
48 (est from graph)
Wt gm-detail:
109.2 g
Water temp (°C)-detail:
7.9 +/- 0.2 C
Dosage-detail:
10 mg/kg sd
Method:
Rad
Authors-red:
Martinsen B, Horsberg TE, Ingebrigtsen K, Gross IL
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