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U.S. Department of Health and Human Services

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Title:  Dynamical coupling of PBPK/PD and AUC-based toxicity models for arsenic in tilapia Oreochromis mossambicus from blackfoot disease area in Taiwan.
 
Authors:  Liao C-M, Liang H-M, Chen B-C, Singh S, Tsai J-W, Chou Y-H, Lin W-T
 
Drug:  Arsenic
 
Fish species:  Tilapia, Mozambique
 
Date:  2005
 
Sample:  liver
 
Ave Weight (gm):  149
 
Ave Water temp (°C):  24
 
Water:  Freshwater
 
Dosage:  1.0 ug/ml 7d
 
Route:  BATH
 
Comments:  Accumulation phase: d1=0.75, d2=0.75, d4= 1.5, d7=2.25 ug/g. Depuration phase d5=1.75, d8=0.75 ug/g.
 
Citation:  Environmental Pollution 135:1221-233
 
Link:  http://dx.doi.org/10.1016/j.envpol.2004.11.005  Opens a new window
 
Genus Species:  Oreochromis mossambicus
 
Drug Class:  Metal-Arsenic
 
Wt gm-detail:  148.72+/-6.5 g
 
Water temp (°C)-detail:  24.3+/-0.32 C
 
Dosage-detail:  1.0 ug/ml for 7 d
 
Method:  AAS
 
Authors-red:  Liao C-M, Liang H-M, Chen B-C, Singh S, Tsai J-W, Chou Y-H, Lin W-T
 
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