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Title:
Total residue depletion and metabolic profile of selected drugs in salmonids: 17±-Methyltestosterone.
Authors:
Hayton WL (1997c)
Drug:
Methyltestosterone
Fish species:
Trout, rainbow
Date:
1997
Sample:
blood, plasma
Ave Weight (gm):
370
Ave Water temp (°C):
12
Water:
Freshwater
Dosage:
30 mg/kg SID 2 or 4 d
Route:
PO
Comments:
Residue by day 2 of treatment was plasma 6.45. Values after 4 days feeding were slightly lower. Depuration was fastest from bile, followed by liver, muscle, kidney, plasma, and skin; after 20 d depuration, total residues were less than 0.10 ppm in plasma. Methyltestosterone (17±) (14C).
Metabolites:
Hydroxymethlytestosterone (HMT), unidentified metabolites.
Citation:
Final FDA Report. Contract 223-93-7014. Vol 2.
Link:
none
Genus Species:
Oncorhynchus mykiss
Drug Class:
Hormone-Testosterone
Wt gm-detail:
370 +/- 73.6 g
Water temp (°C)-detail:
12 C
Dosage-detail:
30 mg/kg once a day for 2 or 4 days
Method:
HPLC-Rad
Authors-red:
Hayton WL (1997c)
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