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Title:
Pharmacokinetics of sulphamonomethoxine in cultured yellowtail after oral administration.
Authors:
Ueno R, Uno K, Aoki T
Drug:
Sulfamonomethoxine
Fish species:
Amberjack, Japanese (yellowtail)
Date:
1994
t1/2-hr:
3
Sample:
kidney
Ave Weight (gm):
357
Ave Water temp (°C):
22
Water:
Saltwater
Dosage:
400 mg/kg sd
Route:
PO
Comments:
T1/2 field=parent. No SMM detected 2d after administration. Residues 0.5h=43, 1h=72, 3h=104, 6h=61, 9h=26, 12h=10, 24h=1, 2d-20d nd ug/g. Glucuronide-SMM metabolite residues at Tmax(3h) =4.2, at 20d=nd; Glucuronide-AcSMM at Tmax(3h) =3.7 ug/g, at 20d=nd.
Metabolites:
N4-acetyl-Sulfamonomethoxine, glucronide conjugate
Citation:
Food Research International 27:33-37
Dep-time:
1.5d
Link:
http://dx.doi.org/10.1016/0963-9969(94)90175-9
Genus Species:
Seriola quinqueradiata
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
3.09 h =parent
Wt gm-detail:
357 g
Water temp (°C)-detail:
22 C
Dosage-detail:
400 mg/kg sd
Method:
HPLC
Authors-red:
Ueno R, Uno K, Aoki T
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