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Title:
The distribution of [14 C]acrylamide in rainbow trout studied by whole-body audioradiography.
Authors:
Waddell WJ, Lech JJ, Marlowe C, Kleinow KM, Friedman MA
Drug:
Acrylamide
Fish species:
Trout, rainbow
Date:
1990
Sample:
whole body
Ave Weight (gm):
7
Ave Water temp (°C):
12
Water:
Freshwater
Dosage:
3.2 mg/kg (0.1µCi/g) sd
Route:
IP
Comments:
22 h after dosing, fish had acrylamide in the blood, lens of eye, gallbladder, intestinal contents, kidney, and bladder. Lesser present in CNS, liver, oral cavity, gastric mucosa, and gills. Minimal quantities in muscle. At 120 hours after dosing most radioactivity had disappeared from the blood, but some remained in gallbladder, intestinal contents, lens of eye, melanin in eye, melanophores in subcutaneous tissue, and vetebrae. CNS and muscle only slightly labeled. 14C-Acrylamide
Citation:
Fundamental and Applied Toxicology 14:84-87
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2307324&dopt=Abstract
Genus Species:
Oncorhynchus mykiss
Drug Class:
Organic-Amide
Wt gm-detail:
7
Water temp (°C)-detail:
12 C
Dosage-detail:
3.2 mg/kg (0.1µCi/g) sd
Method:
Rad
Authors-red:
Waddell WJ, Lech JJ, Marlowe C, Kleinow KM, Friedman MA
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