• Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail

  • Print
  • Share
  • E-mail
-
 
Title:  The distribution of [14 C]acrylamide in rainbow trout studied by whole-body audioradiography.
 
Authors:  Waddell WJ, Lech JJ, Marlowe C, Kleinow KM, Friedman MA
 
Drug:  Acrylamide
 
Fish species:  Trout, rainbow
 
Date:  1990
 
Sample:  whole body
 
Ave Weight (gm):  7
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  3.2 mg/kg (0.1µCi/g) sd
 
Route:  IP
 
Comments:  22 h after dosing, fish had acrylamide in the blood, lens of eye, gallbladder, intestinal contents, kidney, and bladder. Lesser present in CNS, liver, oral cavity, gastric mucosa, and gills. Minimal quantities in muscle. At 120 hours after dosing most radioactivity had disappeared from the blood, but some remained in gallbladder, intestinal contents, lens of eye, melanin in eye, melanophores in subcutaneous tissue, and vetebrae. CNS and muscle only slightly labeled. 14C-Acrylamide
 
Citation:  Fundamental and Applied Toxicology 14:84-87
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2307324&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Amide
 
Wt gm-detail:  7
 
Water temp (°C)-detail:  12 C
 
Dosage-detail:  3.2 mg/kg (0.1µCi/g) sd
 
Method:  Rad
 
Authors-red:  Waddell WJ, Lech JJ, Marlowe C, Kleinow KM, Friedman MA
 
-
-