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Title:  A Physiologically Based Pharmacokinetic Model for Predicting the Withdraw Period of Oxytetracycline in Cultured Chinook Salmon (Oncorhynchus tshawytscha).
 
Authors:  Law FCP (1999)
 
Drug:  Oxytetracycline
 
Fish species:  Salmon, chinook
 
Date:  1999
 
t1/2-hr:  336
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  0
 
Ave Water temp (°C):  9
 
Water:  Saltwater
 
Dosage:  Not Specified
 
Route:  Not Specified
 
Comments:  Authors developed a 9-compartment PK model for predicting of OTC in Chinook Salmon. Authors validated model using data from Namadari et al.(1996). Model predictied withdraw period (WP) of OTC. 60d at 9C and 49d at 15C. T1/2 est from graph of model data.
 
Citation:  In: D.J. Smith, W.H. Gingerich and M.G. Beconi-Barker (Eds.). Xenobiotics in Fish. Kluwer Academic/Plenum Publishers. pp. 105-121
 
Link:  none  Opens a new window
 
Genus Species:  Oncorhynchus tshawytscha
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  336h est from graph of model data
 
Wt gm-detail:  Not Specified
 
Water temp (°C)-detail:  9 C
 
Method:  PK, model
 
Authors-red:  Law FCP (1999)
 
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