Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Residues of MS-222, benzocaine and their metabolites in striped bass following anesthesia.
 
Authors:  Luhning CW
 
Drug:  MS-222
 
Fish species:  Bass, striped
 
Date:  1973
 
t1/2-hr:  1
 
est:  est
 
Sample:  whole body-minus head, scales, viscera, fins
 
Ave Weight (gm):  68
 
Ave Water temp (°C):  19
 
Water:  Freshwater
 
Dosage:  100 mg/l 30 min
 
Route:  BATH
 
Comments:  Tricaine methane sulphonate, t1/2 est. from chart. Mean residues (ug/ g) free ms-222 residues at withdrawal time 0 h = 22.1, 15 min = 13.2, 30 min = 12.3, 45 min=7.8, 60 min = 5.6, m-aminobenzoic acid residue at withdrawal time 0 h = 19.4, 15 min 17.8,30 min=11.6, 45 min=11.6, 60 min = 94. MS222- N-acetyl derivative 0 h= 0.0, 15 min = 0.0, 30 min = 0.0, 45 min=0.5, 60 min = 0.0, m-aminobenzoic acid-N-acetyl derviative residue 0h=3.1, 15 min=2.2, 30 min = 2.0, 45 min=1.5, 60 min=1.6. Levels dropped significantly after storage of samples for 1 week at 1.7 C.
 
Metabolites:  m-aminobenzoic acid and acetylated metabolites
 
Citation:  Investigations in Fish Control. U.S. Dept. of the Interior, Fish and Wildlife Service, Bureau of Sport Fisheries and Wildlife. SH157.7.I58 no.52
 
Link:  none  Opens a new window
 
Genus Species:  Morone saxatilis
 
Drug Class:  Anesthetic-Tricaine
 
t1/2-detail:  <1 h
 
Wt gm-detail:  67.6 g
 
Water temp (°C)-detail:  18 +/- 0.5 C
 
Dosage-detail:  100 mg/l 30 min
 
Method:  Absorbance-Bratton&Marshall, TLC
 
Authors-red:  Luhning CW
 
-
-