Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Effect of temperature on pharmacokinetics of enrofloxacin in mud crab, Scylla serrata (forsskal), following oral administration.
 
Authors:  Fang WH, Hu LL, Yang XL, Hu K, Liang SC, Zhou S
 
Drug:  Enrofloxacin
 
Fish species:  Crab, mud
 
Date:  2008
 
t1/2-hr:  57
 
Sample:  blood, hemolymph
 
Ave Weight (gm):  135
 
Ave Water temp (°C):  26
 
Water:  Brackish
 
Dosage:  10 mg/kg sd
 
Route:  PO
 
Comments:  t1/2 alpha=1.5, Cmax=11.03 ug/ml, tmax 2 h, t1/2ka=1. 1, AUC 583.4 mg/L/h. Residues 0.5h=8.6, 1h=9.96, 2h=11, 4h=9.8, 6h=7.8, 12h=5.9, 24h=5.0, 48 h=4.5, 96h=1.9, 144h=1, 192h=0.5. MRT=63.7 h.
 
Cl:  0.018
 
Vd:  1.111
 
Citation:  J Fish Diseases 31:171-176
 
Link:  http://fdamedlibmd.library.ingentaconnect.com/content/bsc/jfd/2008/00000031/00000003/art00002  Opens a new window
 
Genus Species:  Scylla serrata
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  56.5 h
 
Wt gm-detail:  120-150 g
 
Water temp (°C)-detail:  26+/-0.5 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Fang WH, Hu LL, Yang XL, Hu K, Liang SC, Zhou S
 
-
-