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Title:
Astaxanthin and Canthaxanthin kinetics after ingestion of individual doses by immature rainbow trout Oncorhynchus mykiss.
Authors:
Gobantes I, Choubert G, Laurentie M, Milicua JCG, Gomez R
Drug:
Canthaxanthin
Fish species:
Trout, rainbow
Date:
1997
t1/2-hr:
13
Sample:
blood, serum
Ave Weight (gm):
300
Ave Water temp (°C):
20
Water:
Freshwater
Dosage:
100 ug sd
Route:
PO
Comments:
Of 234 fish dosed, 5 did not show a serum response to carotenoid pigments. Max 2.9 nmol/ml 12 h post dose. Rapid decrease in residue between 12-42 hr. 42 h- near baseline residue. (0-0.5 nmol/ml). Mean retention time=23.1 h. AUC 52.9 ug h/ ml. Only detected in intestin up to 12 hrs (0.3 nmol/gm), not detected in liver.
Citation:
J. Agricultural and Food Chemistry 45:454-458
Link:
http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/1997/45/i02/abs/jf9604605.html
Genus Species:
Oncorhynchus mykiss
Drug Class:
Organic-Carotenoid
t1/2-detail:
12.63 h
Wt gm-detail:
300 g
Water temp (°C)-detail:
20+/-0.5 C
Dosage-detail:
100 ug 5% water-sol beadlets in meal-sd
Method:
HPLC
Authors-red:
Gobantes I, Choubert G, Laurentie M, Milicua JCG, Gomez R
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