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U.S. Department of Health and Human Services

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Title:  Rapid loss of Lampricide from Catfish and Rainbow trout following routine treatment.
 
Authors:  Dawson VK, Schreier TM, Boogaard MA, Spanjers NJ, Gingerich WH
 
Drug:  Niclosamide-(2,5-Dichloro-4-nitrosalicylanilide)
 
Fish species:  Trout, rainbow
 
Date:  2002
 
t1/2-hr:  7
 
est:  est
 
Sample:  muscle+skin
 
Ave Weight (gm):  300
 
Ave Water temp (°C):  18
 
Water:  Freshwater
 
Dosage:  0.02 mg/l 12 h
 
Route:  BATH
 
Comments:  Stream cage study. Residues decreased rapidly after the block of lampricide had passed and was below the detection limit in fillet within 24 h after arrival of lampricide (Bayluscide used TFM was given higher upstream). Max residue 0.0395 ug/g at 12 hr. Metabolites found in previous studies not found in this study.
 
Metabolites:  glucuronide, conjugate, sulfate ester
 
Citation:  J. Agricultural Food Chemistry 50:6780-6785
 
Dep-time:  24 hrs
 
Link:  http://pubs.acs.org/doi/abs/10.1021/jf020443h  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antiparasitic-Niclosamide
 
t1/2-detail:  7 hr est form graph
 
Wt gm-detail:  200-400 g
 
Water temp (°C)-detail:  18.3+/-1.5 C
 
Dosage-detail:  0.02 mg/l for 12 h, nominal. 0.176 measured at 6 hr.
 
Method:  HPLC
 
Authors-red:  Dawson VK, Schreier TM, Boogaard MA, Spanjers NJ, Gingerich WH
 
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