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Title:
Pharmacokinetic studies of florfenicol in Koi carp and Threespot gourami Trichogaster trichopterus after oral and intramuscular treatment
Authors:
Yanong RPE, Curtis EW, Simmons R, Bhattaram VA, Gopalakrishnan M, Ketabi N, Nagaraja NV, Derendorf H
Drug:
Florfenicol
Fish species:
Carp, common (koi)
Date:
2005
t1/2-hr:
16
Sample:
blood, plasma
Ave Weight (gm):
144
Ave Water temp (°C):
24
Water:
Freshwater
Dosage:
50 mg/kg sd
Route:
PO
Comments:
Ka- absorption 0.5/h, Non compartmental analysis C max=12.3 h, Tmax=3 h, AUC=262.6 ug/h//ml, t1/2=7.6 h.
Cl:
0.05 L/kg/h
Vd:
1.03 L/kg
Citation:
J. Aquatic Animal Health 17:129-137
Link:
http://afs.allenpress.com/perlserv/?request=get-abstract&doi=10.1577%2FH03-065.1
Genus Species:
Cyprinus carpio
Drug Class:
Antibiotic-Phenicol
t1/2-detail:
15.8
Wt gm-detail:
144+/-44 g
Water temp (°C)-detail:
23-25 C
Dosage-detail:
50 mg/kg sd
Method:
HPLC
Authors-red:
Yanong RPE, Curtis EW, Simmons R, Bhattaram VA, Gopalakrishnan M, Ketabi N, Nagaraja NV, Derendorf H
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