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U.S. Department of Health and Human Services

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Title:  Comparative uptake of orally administered difloxacin in Atlantic salmon in freshwater and seawater.
 
Authors:  Elston RA, Drum AS, Schweitzer MG, Rode RA, Bunnell PR
 
Drug:  Difloxacin
 
Fish species:  Salmon, Atlantic
 
Date:  1994
 
t1/2-hr:  16
 
est:  est
 
Sample:  blood, plasma
 
Ave Weight (gm):  190
 
Ave Water temp (°C):  11
 
Water:  Saltwater
 
Dosage:  10 mg/kg sd
 
Route:  PO
 
Comments:  Seawater, difloxacin concentration increased to a peak average of 678 ng/ml at 8 h, then decreased to 212 ng/ml at 48h
 
Citation:  J. Aquatic Animal Health 6: 341-348
 
Link:  http://www.tandfonline.com/doi/abs/10.1577/1548-8667%281994%29006%3C0341%3ACUOOAD%3E2.3.CO%3B2  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  10- 16 hr (est)
 
Wt gm-detail:  juveniles
 
Water temp (°C)-detail:  10.7- 11.9 C seawater
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Elston RA, Drum AS, Schweitzer MG, Rode RA, Bunnell PR
 
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