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Title:
Uptake of erythromycin by first-feeding sockeye-salmon, Oncorhynchus nerka (Walbaum), fed live or freeze-dried enriched adult Artemia or medicated pellets.
Authors:
Cook MA, Rust MB, Massee K, Majack T, Peterson ME
Drug:
Erythromycin
Fish species:
Salmon, sockeye
Date:
2003
t1/2-hr:
96
est:
est
Sample:
whole body
Ave Weight (gm):
45
Ave Water temp (°C):
13
Water:
Freshwater
Dosage:
305.8 mg/kg 21 d
Route:
PO
Comments:
Live Artemia. Erythromycin concentration in tissues of the fish fed live Artemia was higher than those fed pellets. No difference found between live or freeze-dried Artemia. Uptake of bioencapsulated erythromycin from Artemia greater uptake than from pellets. residue 10.58 ug/ml at end of dosing. Erythromycin not detectable after 9d. t 1/2 est from table.
Citation:
J. Fish Diseases 26:277-285
Dep-time:
9 d
Link:
http://www.ncbi.nlm.nih.gov/pubmed/12962236
Genus Species:
Oncorhynchus nerka
Drug Class:
Antibiotic-Macrolide
t1/2-detail:
< 96 hr est
Wt gm-detail:
45 g
Water temp (°C)-detail:
12.4-13.7 C
Dosage-detail:
305.8+/-24.4 ug/g for 21 d
Method:
Micro
Authors-red:
Cook MA, Rust MB, Massee K, Majack T, Peterson ME
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