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U.S. Department of Health and Human Services

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Title:  Uptake of erythromycin by first-feeding sockeye-salmon, Oncorhynchus nerka (Walbaum), fed live or freeze-dried enriched adult Artemia or medicated pellets.
Authors:  Cook MA, Rust MB, Massee K, Majack T, Peterson ME
Drug:  Erythromycin
Fish species:  Salmon, sockeye
Date:  2003
t1/2-hr:  96
est:  est
Sample:  whole body
Ave Weight (gm):  45
Ave Water temp (°C):  13
Water:  Freshwater
Dosage:  305.8 mg/kg 21 d
Route:  PO
Comments:  Live Artemia. Erythromycin concentration in tissues of the fish fed live Artemia was higher than those fed pellets. No difference found between live or freeze-dried Artemia. Uptake of bioencapsulated erythromycin from Artemia greater uptake than from pellets. residue 10.58 ug/ml at end of dosing. Erythromycin not detectable after 9d. t 1/2 est from table.
Citation:  J. Fish Diseases 26:277-285
Dep-time:  9 d
Link:  http://www.ncbi.nlm.nih.gov/pubmed/12962236  Opens a new window
Genus Species:  Oncorhynchus nerka
Drug Class:  Antibiotic-Macrolide
t1/2-detail:  < 96 hr est
Wt gm-detail:  45 g
Water temp (°C)-detail:  12.4-13.7 C
Dosage-detail:  305.8+/-24.4 ug/g for 21 d
Method:  Micro
Authors-red:  Cook MA, Rust MB, Massee K, Majack T, Peterson ME