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U.S. Department of Health and Human Services

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Title:  A single-dose pharmocokinetic study of emamectin benzoate in cod, Gadus morhua L., held in sea water at 9C.
 
Authors:  Samuelsen OB
 
Drug:  Emamectin Benzoate
 
Fish species:  Cod, Atlantic
 
Date:  2010
 
t1/2-hr:  235
 
Sample:  skin
 
Ave Weight (gm):  150
 
Ave Water temp (°C):  9
 
Water:  Saltwater
 
Dosage:  0.05 mg/kg sd
 
Route:  PO
 
Comments:  Salinity at 33 ppt. Fish anesthetized by immersion in metomidate (5 mg/L). Fish killed by blow to the head. Cmax=28ng/g, Tmax=72h, Bioavailability=38%.
 
Citation:  J. Fish Diseases 33:137-142
 
Link:  http://dx.doi.org/10.1111/j.1365-2761.2009.01097.x  Opens a new window
 
Genus Species:  Gadus morhua
 
Drug Class:  Antiparasitic-Avermectin
 
t1/2-detail:  235h
 
Wt gm-detail:  100-200g
 
Water temp (°C)-detail:  9.0+/-0.5C
 
Dosage-detail:  50 ug/kg sd
 
Method:  HPLC
 
Authors-red:  Samuelsen OB
 
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