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U.S. Department of Health and Human Services

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Title:  Blood concentrations of tricaine methane sulphonate in Brook trout, Salvelinus fontinalis, during anesthetization, branchial irrigation, and recovery.
 
Authors:  Houston AH, Woods RJ (1972)
 
Drug:  MS-222
 
Fish species:  Trout, brook
 
Date:  1972
 
t1/2-hr:  2
 
est:  est
 
Sample:  blood
 
Ave Weight (gm):  415
 
Ave Water temp (°C):  4
 
Water:  Freshwater
 
Dosage:  100 mg/l
 
Route:  BATH
 
Comments:  Tricaine methane sulphonate. Blood levels (mg/l) = approx 55 during induction using 100 mg/l solution. Maintenance at 50 mg/l for 15 min = blood level of 67 mg/l, at 100 mg/l = blood level of 114 mg/l. Equilibrium when transferred to recovery 25 mg/l. Clearance blood levels (mg/l) 1 hr = 16.7, 2 hr = 6.2, 3 hr = 6.2, 6 hr= 4.5, 612hr = 4.3, 24 hr = 4.1.
 
Cl:  50% Cl=20 min. 90% Cl=55 min
 
Citation:  J. Fisheries Research Board of Canada 29:9:1344-1346.
 
Link:  none  Opens a new window
 
Genus Species:  Salvelinus fontinalis
 
Drug Class:  Anesthetic-Tricaine
 
t1/2-detail:  < 2 hr
 
Wt gm-detail:  366.4-465.9
 
Water temp (°C)-detail:  3.5-5 C
 
Dosage-detail:  100 mg/l
 
Method:  Absorbance-Bratton&Marshall
 
Authors-red:  Houston AH, Woods RJ (1972)
 
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