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Title:
Enrofloxacin pharmacokinetics in the European cuttlefish, Sepia officinalis, after a single i.v. injection and bath administration.
Authors:
Gore SR, Harms CA, Kukanich B, Forsythe J, Lewbart GA, Papich MG
Drug:
Enrofloxacin
Fish species:
Cuttlefish, European common
Date:
2005
t1/2-hr:
1
Sample:
blood, hemolymph
Ave Weight (gm):
113
Ave Water temp (°C):
25
Water:
Saltwater
Dosage:
10 mg/kg sd
Route:
PO
Comments:
Cipro metabolite was not found. Salinity 32%. Hemolymph sampling -before dose, 3 at times1,3, 6, 24, 48.Tmax=1 h, Cmax=10.85 ug/ml, AUC=26.71 ug.h/ml, MRT 1.94 h.
Metabolites:
Ciprofloxacin
Citation:
J. Veterinary Pharmacology and Therapeutics 28:433-439
Link:
http://dx.doi.org/10.1111/j.1365-2885.2005.00684.x
Genus Species:
Sepia officinalis
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
1.01 h
Wt gm-detail:
95.7and 129.7g
Water temp (°C)-detail:
25 C
Dosage-detail:
10 mg/kg sd
Method:
HPLC
Authors-red:
Gore SR, Harms CA, Kukanich B, Forsythe J, Lewbart GA, Papich MG
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