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U.S. Department of Health and Human Services

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Title:  Absolute oral bioavailability and residues of florenicol in rainbow trout (Onchorynchus mykiss).
 
Authors:  Pinault LP, Millot LK, Sanders PJ
 
Drug:  Florfenicol
 
Fish species:  Trout, rainbow
 
Date:  1997
 
t1/2-hr:  72
 
est:  est
 
Sample:  muscle+skin
 
Ave Water temp (°C):  10
 
Water:  Freshwater
 
Dosage:  10 mg/kg 10 d
 
Route:  PO
 
Comments:  Fish received 1.1 mg (at 8.4 mg/kg) this their weight is presumed to be aprox 130 gm. Residues of Florfenicol amine ug/g 12 h=3.95, 1d=3.37, 3d=1.08, 8d=0.21, 15d=0.15, 22d&29d=
 
Metabolites:  Florfenicol amine
 
Citation:  J. Veterinary Pharmacology and Therapeutics 20 (supp 1):297-317.
 
Dep-time:  80 deg day
 
Link:  http://agris.fao.org/agris-search/search/display.do?f=1998%2FGB%2FGB98010.xml%3BGB1997029686  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Phenicol
 
t1/2-detail:  < 3d est from table
 
Wt gm-detail:  130 g*
 
Water temp (°C)-detail:  10 +/- 1C
 
Dosage-detail:  10 mg/kg 10 d
 
Method:  HPLC
 
Authors-red:  Pinault LP, Millot LK, Sanders PJ
 
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