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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Oral single-dose pharmacokinetics of thiamphenicol in the sea-bass (Dicentrarchus labrax).
 
Authors:  Castells G, Intorre L, Bertini S, Cristofol C, Soldani G, Arboix M
 
Drug:  Thiamphenicol
 
Fish species:  Seabass, European
 
Date:  2000
 
t1/2-hr:  20
 
est:  est
 
Sample:  blood, plasma
 
Ave Weight (gm):  275
 
Ave Water temp (°C):  0
 
Water:  Not Specified
 
Dosage:  15 mg/kg sd
 
Route:  PO
 
Comments:  1 ml/kg solution with 15 mg/kg TAP, = final dose 15 mg/kg sd, t 1/2 estimated from graph. AUC 54 ug.h/ml.
 
Citation:  J. Veterinary Pharmacology and Therapeutics 23:53-54
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10747244&dopt=Abstract  Opens a new window
 
Genus Species:  Dicentrarchus labrax
 
Drug Class:  Antibiotic-Phenicol
 
t1/2-detail:  15-20 h est
 
Wt gm-detail:  250-300
 
Water temp (°C)-detail:  Not Specified
 
Dosage-detail:  1 ml/kg solution with 15 mg/kg TAP, = final dose 15 or 30 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Castells G, Intorre L, Bertini S, Cristofol C, Soldani G, Arboix M
 
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