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Title:
Pharmacokinetic and pharmacodynamic properties of Metomidate in turbot (Scophthalmus maximus) and halibut (Hippoglossus hippoglossus).
Authors:
Hansen MK, Nymoen U, Horsberg TE
Drug:
Metomidate
Fish species:
Halibut, Atlantic
Date:
2003
t1/2-hr:
6
Sample:
blood, plasma
Ave Weight (gm):
166
Ave Water temp (°C):
10
Water:
Brackish
Dosage:
3 mg/kg sd
Route:
IV
Comments:
Brackish water - salinity 3%
Cl:
0.099 L/kg/h
Vd:
0.21 L/kg
Citation:
J. Veterinary Pharmacology and Therapeutics 26:95-103
Link:
http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2885.2003.00454.x/abstract
Genus Species:
Hippoglossus hippoglossus
Drug Class:
Anesthetic-Metomidate
t1/2-detail:
5.8 h
Wt gm-detail:
166+/-47 g
Water temp (°C)-detail:
10.3+/-0.5 C
Dosage-detail:
3 mg/kg sd
Method:
HPLC
Authors-red:
Hansen MK, Nymoen U, Horsberg TE
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