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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Disposition of benzocaine in catfish.
 
Authors:  Szoke A, Kemmenoe BH, Hayton WL
 
Drug:  Benzocaine
 
Fish species:  Catfish, channel
 
Date:  1994
 
t1/2-hr:  192
 
Sample:  kidney, cranial
 
Ave Weight (gm):  0
 
Ave Water temp (°C):  0
 
Water:  Freshwater
 
Dosage:  105 mg/l 35 min
 
Route:  BATH
 
Comments:  70 ppm bath for 5 min, followed by 35 ppm bath for 30 min.Benzocaine (14)C. Residue reached about 1% of 0 depuration level after 25 hr. After 4 hr N-acetylbenzocaine became major metabolite.
 
Metabolites:  p-acetaminobenzoic acid, N-acetylbenzocaine
 
Citation:  Pharmaceutical Research 11:10:S-384
 
Link:  none  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Anesthetic-Benzocaine
 
t1/2-detail:  192 h est by author
 
Wt gm-detail:  Not specified
 
Water temp (°C)-detail:  Not specified
 
Dosage-detail:  70 ppm bath for 5 min, followed by 35 ppm bath for 30 min.
 
Method:  HPLC/RP, HPLC-Rad
 
Authors-red:  Szoke A, Kemmenoe BH, Hayton WL
 
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