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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Renal excretion of tetracycline in the aglomerular toadfish, Opsanus tau.
 
Authors:  Fanelli G Jr, Nigrelli RF
 
Drug:  Tetracycline
 
Fish species:  Toadfish, oyster
 
Date:  1963
 
Sample:  blood
 
Ave Weight (gm):  298
 
Ave Water temp (°C):  0
 
Water:  Saltwater
 
Dosage:  5-50 mg/kg
 
Route:  IM
 
Comments:  (3)H tetracycline. Excretion (15% in 24 hr) appears to be by diffusion from peritubular blood to tubular urine. Thought to be passive diffusion, but no data on protein binding. Plotted plasma vs urine tetracycline, linear relationship.
 
Citation:  Proceedings of the Society of Experimental Biology 114:582-584
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14115261  Opens a new window
 
Genus Species:  Opsanus tau
 
Drug Class:  Antibiotic-Tetracycline
 
Wt gm-detail:  155-440 g
 
Water temp (°C)-detail:  Not Specified
 
Dosage-detail:  5-50 mg/kg
 
Method:  Rad
 
Authors-red:  Fanelli G Jr, Nigrelli RF
 
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